Upper extremity fracture
Conditions
Interventions
ketamine1.0 group : ketamine 1.0 mg/kg + 0.2 mg/kg(Additional doses every hour)
ketamine0.5 group : ketamine 0.5 mg/kg + 0.1mg/kg(Additional doses every hour)
Ketamine is administered at 1.0 mg/kg or
Sponsors
Kamiya Takefumi
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Patients over 20 years 2) Patients who receive written informed consent. 3) Patients with American Society of Anesthesiologists physical status classification 1-3.
Exclusion criteria
Exclusion criteria: 1. Patients who are deemed inappropriate as research subjects by the principal investigator 2. Patients who refuse to participate in the study. 3. Patients who have contraindications to the use of ketamine or contraindications to the use of usual postoperative analgesics such as NSAIDs and acetaminophen, contraindications to local anesthetics, are pregnant or suspected pregnant women, poorly controlled diabetes, vascular disorders (aneurysms), unable to understand the perioperative questionnaire (language or cognitive impairment), severe heart disease, Severe obesity (BMI > 35), patients who have not responded to nerve blocks, emergency surgery.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of Rebound Pain | — |
Secondary
| Measure | Time frame |
|---|---|
| Difference in pain score before and after PNB resolution between the lowest NRS after and the maximum NRS value within 12 hours after loss of action time; NRS values at 2, 4, 6, 12, and 24 hours; total amount of narcotic analgesics used within 24 hours; time of first analgesic use. | — |
Contacts
Public ContactTakefumi Kamiya
Nihon University Itabashi Hospital
Outcome results
None listed