Healthy subjects
Conditions
Interventions
Sponsors
Taida Takashi
Eligibility
Sex/Gender
Male
Inclusion criteria
Inclusion criteria: 1) Subjects who have not undergone upper or lower gastrointestinal surgery. 2) Male subjects who are at least 20 years old and less than 75 years old at the time of consent. 3) Subjects who have been fully informed of the study and who have given their consent in writing of their own free will with full understanding.
Exclusion criteria
Exclusion criteria: 1) Subjects who have received other laxatives within 1 week prior to the start of laxative administration 2) Subjects who are at risk of shock, anaphylaxis after receiving laxatives. 3) Subjects with suspected intestinal obstruction or severe constipation. 4) Subjects with diarrhea or bloody stool. 5) Other subjects who are judged by the investigator or subinvestigator to be unsuitable for the safe conduct of this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| IgA/IgG antibody levels in intestinal lavage fluid and collections at the time of colonoscopy | — |
Secondary
| Measure | Time frame |
|---|---|
| CTB-specific IgA and IgG antibody levels in the samples. Total protein level in the samples. Physical properties analysis of multimeric IgA in the samples. | — |
Contacts
Public ContactTakashi Taida
Chiba University Hospital
Outcome results
None listed