Patients undergoing hepatectomy Rocuronium, Pringle maneuver, muscle relaxant effect, hepatectomy
Conditions
Interventions
None listed
Sponsors
Yamamoto Mai
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Patients 20 years of age or older undergoing hepatectomy under general anesthesia 2) Cases with American Society of Anesthesiologists pre-anesthetic risk assessment 3 or less 3) Patients whose consent to participate in this study is obtained in writing.
Exclusion criteria
Exclusion criteria: 1) Patients who do not meet the above selection criteria 2) Patients with a history of allergy to muscle relaxants 3) Patients with severe systemic complications (American Society of Anesthesiologists Preanesthetic Risk Rating 4 or higher) 4) Obese patients with a BMI of 30 or greater and patients with a body mass index of less than 18.5 5) Patients with neuromuscular diseases 6) Patients with moderate to severe hepatic dysfunction (Child-Pugh classification) 7) Patients who have refused to participate in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Urinary rocuronium concentration before and after hepatic blood flow blockade | — |
Secondary
| Measure | Time frame |
|---|---|
| Plasma Rocuronium Concentration Before and After Hepatic Blood Blockade Rocuronium protein binding before and after hepatic blood flow deprivation Plasma bile acid concentration before and after hepatic blood flow deprivation | — |
Contacts
Public ContactMai Yamamoto
Nihon University School of Medicine
Outcome results
None listed