Hereditary Dementia Hereditary Dementia (Alzheimers disease, Frontotemporal dementia, Lewy body dementia, Vascular dementia, Cerebral white matter dementia, etc.)
Conditions
Interventions
None listed
Sponsors
Yoshiki Sekijima
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Provide written informed consent of their own free will from the patient or a representative. 2. 12 years or older at the time of informed consent. 3. Have a study partner that is willing to participate as a source of information and has approximately weekly contact with the participant (contact can be in-person, via telephone or electronic communication). 4. Approximately healthy without severe current or past medical history which hinder research participation. 5. Have sufficient eyesight and hearing to undergo neuropsychological examinations. 6. Have sufficient Japanese ability.
Exclusion criteria
Exclusion criteria: 1. History within 3 months of psychosis, agitation, or behavior problem which interfere study protocol. 2. Have a history of alcohol or substance use disorder defined by DSM-V within 2 years. 3. In the unstable medical condition judged by the investigator that pose risks or that interfere research result or subject's performance. It includes uncontrolled hypertension, uncontrolled diabetes, clinically serious heart, lung, kidney, liver, endocrine, or systemic disease. 4. History of primary or recurrent malignant cancer within the past 3 years, except for non-melanoma skin cancer, removed squamous cell carcinoma, basal cell carcinoma, cervical intraepithelial neoplasia, or non-invasive prostate cancer with normal PSA after treatment. 5. With an ineligibility judged by the principal investigator.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| MMSE, Cognitive function score by CDR-SB | — |
Secondary
| Measure | Time frame |
|---|---|
| Plasma biomarkers | — |
Contacts
Public ContactSekijima Yoshiki
Shinshu University
Outcome results
None listed