Patients undergoing general anesthesia
Conditions
Interventions
Use remimazolam as a sedative. Blood samples are drawn during general anesthesia.
Sponsors
Takagi Shunichi
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Patients whose age is between 20 and 45 years old or between 70 and 91 years old 2. Patients with an American Society of Anesthesiologists pre-anesthesia risk rating of 3 or less 3. Patients who have given consent
Exclusion criteria
Exclusion criteria: 1. Patients with a history of allergy to muscle relaxants or antagonists 2. Patients with severe complications 3. patients with neuromuscular disease 4. Patients taking medications that may affect the effect of muscle relaxation. 5. Patients who are deemed inappropriate as research subjects by the principal investigator 6. Patients who refuse to participate in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| PTC appearance time in the young and elderly groups | — |
Secondary
| Measure | Time frame |
|---|---|
| T1 and T2 appearance time Time until TOF ratio reaches 100% after sugammadex administration PTC, blood rocuronium/remimazolam concentration at T1 and T2 appearance, and rocuronium protein binding rate | — |
Contacts
Public ContactShunichi Takagi
Nihon University School of Medicine, Department of Anesthesiology
Outcome results
None listed