idiopathetic sudden sensorineuronal hearing loss and acute low-tone sensorineural hearing loss ISSNHL, ALHL
Conditions
Interventions
Randomized controlled trial of steroid dose
High-dose steroid administration group. start dose of prednisolone is 30mg. Tapering off in 9 days.
Low-dose steroid administration group. start dose of pr
Randomized Controlled Trial
Sponsors
Hyakusoku Hiroshi
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Within 2 weeks of the first onset of idiopathic sudden sensorineural hearing loss and acute low-tone sensorineural hearing loss 2. Not treated with steroids 3. Obtained written informed consent
Exclusion criteria
Exclusion criteria: 1. Patients who are contraindications or relative contraindications to administration of test drug, prednisolone and dexamethasone. 2. A case of ipsilateral sensorineural hearing loss in the past. (presbycusis is not included.) 3. If there is a disease in the middle ear or outer ear at the time of contract the disease, and pure tone audiometry shows that the average (250, 500, 1000, 2000 and 4000 Hz) of air-bone gap differences is 10 dB or more. 4. Among cases in which the contralateral ear has suffered from ear disease in the past and presents with hearing loss, there is no pure tone audiometry (within the past 5 years) before the contract the disease. 5. A case that develops with sudden hearing loss and is found to be another disease by subsequent scrutiny and progress.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Improvement rate of idiopathetic sensorineuronal hearing loss and acute low-tone sensorineural hearing loss | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of adverse event | — |
Contacts
Public ContactHiroshi Hyakusoku
Yokosuka Kyosai Hospital
Outcome results
None listed