Laboratory tests to support the clinical diagnosis of anaphylaxis in healthy volunteers

Skin testing and in vitro allergy tests in healthy volunteers to establish the method for determining causative drug of perioperative anaphylaxis and improve the accuracy of in vitro allergy tests: A preliminary study

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-jRCT1031210569

Enrollment

Registered

2022-01-21

Start date

2022-01-21

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

anaphylaxis anaphylaxis

Interventions

Perform a prick test and an intradermal test to confirm the negative for the drug. Blood is collected and the control value in the in-vitro test is measured.

D012882

skin testing

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) A volunteer who is 20 years or older 2) A volunteer whose written consent has been obtained regarding participation in this study

Exclusion criteria

Exclusion criteria: 1)A pregnant woman /A patient who has a possibility of pregnancy 2)A volunteer taking beta-blocker 3)A volunteer taking steroid 4)A volunteer with a history of perioperative anaphylaxis 5)A volunteer who cannot stop taking antihistamines

Design outcomes

Primary

Measure	Time frame
Seeking the optimum concentrations of drugs for in vitro tests.	—

Secondary

Measure	Time frame
Exploring the methods which improve the accuracies of in vitro tests.	—

Contacts

Public ContactTomonori Takazawa

Gunma University Hospital

takazawt@gunma-u.ac.jp+81-27-220-8698

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026