Non-emergency patients undergoing surgery under general anesthesia
Conditions
Interventions
Subjects are given 100% oxygen at 6 L / min through a face mask for at least 3 minutes, and then sedation is started. In the Remimazolam group (group R), Remimazolam is stated at 12 mg/kg/hr. In the p
Sponsors
Okuda Yasuhisa
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Patients with written consent to participate in this study. 2) Patients aged between 20 and 65 at the time of consent. 3) American Society of Anesthesiologists (ASA) Grade I or II patients. 4) Patients whose surgical purpose is other than heart surgery.
Exclusion criteria
Exclusion criteria: 1) Patients undergoing emergency surgery. 2) Patients who may be pregnant. 3) Patients who are expected to have difficulty airway management or intubation. 4) BMI 28 and above. 5) Patients who have high risk of aspiration. 6) Patients with liver dysfunction: Child-pugh classification B or higher. 7) Patients with contraindications to propofol or remimazolam. 8) Patients with a history of alcoholism or drug abuse. 9) Patients who regularly use sedatives. 10) Patients with a history of cervical spine / cervical cord disease. 11) Patients with no eyelashes. 12) Patients with a history of cranial nerve system disease.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The proportion of subjects with the loss of jaw thrust reflex. | — |
Secondary
| Measure | Time frame |
|---|---|
| The dose of Remimazolam required for the loss of jaw thrust reflex. The dose of Remimazolam required for the loss of eyelash reflex. Bispectral Index (BIS) value at the time of the loss of jaw thrust reflex. | — |
Contacts
Public ContactHayato Arime
Dokkyo Medical University Saitama Medical Center
Outcome results
None listed