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The efficacy of medium-chain fatty acid oil diet

Evaluation of the safety and efficacy of medium-chain fatty acid oil diet in patients with liver cirrhosis and hepatocellular carcinoma

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-jRCT1031210329
Enrollment
90
Registered
2021-09-22
Start date
2021-09-06
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Liver cirrhosis, Hepatocellular carcinoma LC HCC

Interventions

Ingested ingredients: MCT oil Dosage: Start with 6g at a time and take 30-36g / day (10-12g / meal) daily. Intake period: 3 months Nutritional guidance and intake situation, the confirmation of the sy

Sponsors

Sakaki Masashi
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1) Patients with liver cirrhosis or hepatocellular carcinoma who are visiting the Department of Gastroenterology, Showa University Hospital. 2) Patients with albumin 4.0 mg / dL or less. 3) Patients who are 20 years of age or older at the time of obtaining consent. 4) Patients who have given written consent to participate in this study.

Exclusion criteria

Exclusion criteria: 1) Patients with uncontrolled hepatic encephalopathy. 2) Patients who require ascites puncture (twice or more a month). 3) Decompensated cirrhosis in patients with T-Bil of 3 or higher or in Child-Pugh classification grade C. 4) Patients who are judged to be ineligible by the judgment of the research doctor.

Design outcomes

Primary

MeasureTime frame
Improvement of albumin level, prealbumin level, and retinol-binding protein by MCT diet

Secondary

MeasureTime frame
Evaluation of liver function (Child-Pugh score, ALBI-grade) Evaluation of amino acid balance (Fischer ratio) Evaluation of lipid composition Evaluation of muscle mass Evaluation of body composition

Contacts

Public ContactMasashi Sakaki

Showa University

msakaki@med.showa-u.ac.jp+81-3-3784-8535

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026