Sublingual immunotherapy in preschool children with allergic rhinitis

Randomized trial of efficacy of house dust mite sublingual immunotherapy tablets in preschool children with allergic rhinitis

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-jRCT1031200292

Enrollment

Registered

2021-01-13

Start date

2021-01-13

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Allergic rhinitis Allergic rhinitis

Interventions

Patients aged 1 to 4 years with perennial allergic rhinitis are randomized to the A: intervention group or B: control group. Patients in Group A take a house dust mite sublingual immunotherapy tablet

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1.Patients with perennial allergic rhinitis symptoms 2.Patients with allergic rhinitis who have a specific IgE RAST score of 1 for Dermatophagoides pteronyssinus and D. farinae 3.Diagnosis of perennial allergic rhinitis by a doctor

Exclusion criteria

Exclusion criteria: 1.Patients with severe bronchial asthma 2.Patients with severe atopic dermatitis 3.Patients who have dogs and cats

Design outcomes

Primary

Measure	Time frame
Improvement in nasal and eye symptom scores after 1 year	—

Secondary

Measure	Time frame
1.Improvement in medication scores after 1 year 2.Frequency of adverse reactions 3.Changes in blood variables 4.Sensitization to other inhaled antigens	—

Contacts

Public ContactSakura Sato

National Hospital Organization Sagamihara National Hospital

ssakura8010@foodallergy.jp+81-42-742-8311

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026