A Study on the Effects of Exercise Facility Access on Brain Health

A quasi-experimental prospective study on the effects of exercise facility access on cognitive function

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-jRCT1030250838

Enrollment

160

Registered

2026-03-25

Start date

2026-03-25

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dementias, Mild Cognitive Impairments Dementias, Mild Cognitive Impairments, Cognition, Healthy Aging, prevention & control

Interventions

Intervention group: Participants will receive a 12-month membership to a convenience gym (chocoZAP) free of charge, to provide a low-barrier exercise environment. Control group: No intervention will b

participants will maintain their usual daily activities. As an ethical consideration, an equivalent gym membership will be provided free of charge upon completion of the observation period.

D006293, D000076624, D015444

Heal Promotion, Built Environment, Exercise

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Participants in the Kanagawa Prospective "ME-BYO" Cohort Study 2. Individuals aged 40 years or older residing in Kaisei-town or Matsuda-town at the time of informed consent 3. Capable of independent living 4. Able to communicate in Japanese and complete all required assessments 5. Meeting the following age-specific MMSE score criteria: - Aged 65 years or older: MMSE score >= 18 - Aged 40 to 64 years: MMSE score between 18 and 28 (inclusive)

Exclusion criteria

Exclusion criteria: 1. Individuals with a confirmed diagnosis of dementia by a physician 2. Individuals with severe physical or psychiatric illness that the investigators determine would preclude study participation 3. Individuals with contraindications to MRI (e.g., cardiac pacemaker, claustrophobia) 4. Individuals with a prior history of chocoZAP membership

Design outcomes

Primary

Measure	Time frame
Change in MIREVO cognitive function test score from baseline to the 12-month assessment	—

Secondary

Measure	Time frame
1. Changes in brain structural measures on brain MRI (total brain volume, gray matter volume, white matter volume, hippocampal volume, and white matter hyperintensity volume) 2. Cognitive function assessments (MMSE, MoCA-J, and JART) 3. Self-reported physical activity (IPAQ-based) 4. Physical function (grip strength, gait speed, postural age, body composition, five-times sit-to-stand test, and Timed Up & Go test) > - Quality of life (EQ-5D-5L)	—

Measure

Time frame

1. Changes in brain structural measures on brain MRI (total brain volume, gray matter volume, white matter volume, hippocampal volume, and white matter hyperintensity volume) 2. Cognitive function assessments (MMSE, MoCA-J, and JART) 3. Self-reported physical activity (IPAQ-based) 4. Physical function (grip strength, gait speed, postural age, body composition, five-times sit-to-stand test, and Timed Up & Go test) > - Quality of life (EQ-5D-5L)

—

Contacts

Public ContactSho Nakamura

Kanagawa Cancer Center Research Institute

research@nakasho.org+81-45-520-2222

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026