premenstrual syndrome/ premenstrual dysphoric disorder, presenteeism
Conditions
Interventions
Participants will be randomly assigned, with matching for age and severity of PMS/PMDD symptoms, to one of two groups: a bright light group (8000 lux, n = 26) and a dim light group (800 lux, n = 26).
Sponsors
Kuriyama Kenichi
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: 1) Individuals determined to have PMS/PMDD symptoms based on the Penn Daily Symptom Report (DSR) and the Sheehan Disability Scale (SDISS), defined as having a premenstrual DSR score greater than or equal to 80 and a postmenstrual DSR score at least 50% lower than the premenstrual score, together with at least one SDISS item rated greater than or equal to 4. 2) Individuals aged greater than or equal to 20 and less than 49 years at the time of obtaining informed consent. 3) Female workers with a normal menstrual cycle, defined as a cycle length of 25-38 days with variability within 7 days, and a bleeding duration of 4-7 days with variability within 2 days. 4) Individuals who are able to provide written informed consent for study participation of their own free will.
Exclusion criteria
Exclusion criteria: 1) Workers engaged in night shifts or rotating shift work. 2) Individuals requiring continuous use of psychotropic medications. 3) Individuals requiring off-label medications for the management of menstrual pain. 4) Individuals with ocular or dermatological diseases associated with photosensitivity. 5) Individuals requiring continuous use of female hormone preparations, including oral contraceptives (OC). 6) Individuals requiring continuous use of corticosteroids or immunosuppressive agents. 7) Individuals with general medical conditions that may present with depressive symptoms, such as hypothyroidism, Cushing's syndrome, or systemic lupus erythematosus. 8) Any other individuals judged by the principal or sub-investigator to be inappropriate for participation in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Changes in presenteeism assessed by Work Limitations Questionnaire | — |
Secondary
| Measure | Time frame |
|---|---|
| Changes in Penn Daily Symptom Report (DSR), activity-based sleep monitoring device measures(daytime activity, bedtime, wake-up time, daytime light intensity), Sheehan Disability Scale (SDISS),Pittsburgh Sleep Quality Index (PSQI), Insomnia Severity Index (ISI), Epworth Sleepiness Scale (ESS), SF8 Health Survey (SF-8), Patient Health Questionnaire -9 (PHQ-9), Generalized Anxiety Disorder -7 (GAD-7), and Bedtime Procrastination Scale (BPS) | — |
Contacts
Public ContactAoi Kawamura
National Center of Neurology and Psychiatry
Outcome results
None listed