Paroxysmal atrial fibrillation atrial fibrillation, alcohol, obstractive sleep apnea
Conditions
Interventions
None listed
Sponsors
Iwasaki Yu-ki
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Individuals with non-valvular paroxysmal atrial fibrillation who visit the Department of Cardiovascular Medicine, Nippon Medical School Hospital after the date of study approval. 2. Individuals aged 20 years or older with a habitual alcohol intake, defined as drinking at least 40 g of pure alcohol per week. 3. Individuals who have been provided with an explanation of this study using the informed consent document and have given written consent.
Exclusion criteria
Exclusion criteria: 1. Individuals with long-standing persistent or permanent atrial fibrillation. 2. Individuals who have already been diagnosed with OSA and are receiving continuous positive airway pressure (CPAP) therapy. 3. Women who are pregnant or wish to become pregnant. 4. Individuals whom the principal investigator or co-investigators judge to be unsuitable for participation in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Respiratory Event Index (REI) and Oxygen Desaturation Index (ODI) measured by the portable sleep apnea testing device SAS-2200 REI: The number of respiratory events (apnea and hypopnea) per hour. ODI: The number of episodes per hour in which arterial oxygen saturation decreases by >=3% and returns to baseline within 2 minutes. | — |
Secondary
| Measure | Time frame |
|---|---|
| With the SAS-2200 device: Lowest SpO2 and Average SpO2 according to alcohol consumption status Snoring index Positional analysis Pulse rate variability Associations with ALDH gene polymorphisms With Holter ECG monitoring: Heart rate variability Presence of supraventricular and ventricular arrhythmias | — |
Contacts
Public ContactYu-ki Iwasaki
Nippon Medical School Hospital
Outcome results
None listed