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How Insert Design Affects Leg Muscle Activity After Total Knee Arthroplasty

A Study on the Influence of Insert Design on Lower Limb Muscle Activity in Total Knee Arthroplasty: Comparison Between Medial Stabilized and Cruciate Retaining Inserts

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-jRCT1030250082
Enrollment
5
Registered
2025-05-02
Start date
2025-05-02
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Knee osteoarthritis Knee osteoarthritis, Total knee arthoplasty, Insert, Muscle activity

Interventions

The study will target patients who have undergone bilateral TKA and received different inserts (CR-type and MP-type) in each knee. After performing a resting MRI, the patients will engage in stair asc
MeSH Code: D005205
stair ascent and descent

Sponsors

Hashimoto Shogo
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1) Patients who have undergone bilateral total knee arthroplasty (TKA) for osteoarthritis more than one year ago 2) Patients who received a cruciate-retaining (CR) insert in one knee and a medial-pivot (MP) insert in the other knee 3) Patients who are eligible for MRI examination 4) Outpatients 5) Patients who have provided written informed consent to participate in this study

Exclusion criteria

Exclusion criteria: 1) Patients with inflammatory diseases such as rheumatoid arthritis 2) Patients with secondary knee osteoarthritis due to ligament injury or other causes 3) Patients who are unable to perform stair ascent and descent 4) Patients with missing data on postoperative clinical outcomes or imaging findings

Design outcomes

Primary

MeasureTime frame
Muscle activity will be evaluated using T2 relaxation times obtained from MRI T2 mapping. Regions of interest (ROIs) will be defined for each thigh muscle, and changes in T2 relaxation times between resting and post-exercise MRI will be measured.

Secondary

MeasureTime frame
Quadriceps muscle strength will be measured to evaluate its association with muscle activity.

Contacts

Public ContactShogo Hashimoto

Gunma university hospital

hshou0625@gmail.com+81-272208269

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026