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Exploration of Improving Treatment Outcomes for Gastrointestinal Malignant Tumors by Targeting Oral Environment and Oral Frailty

Exploration of Improving Treatment Outcomes for Gastrointestinal Malignant Tumors by Targeting Oral Environment and Oral Frailty

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-jRCT1030240573
Enrollment
600
Registered
2024-12-20
Start date
2024-11-13
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

gastrointestinal malignant tumors

Interventions

Masticatory Ability Measurement: Using xylitol chewing check gum. Data Measurement: Using a body composition analyzer.

Sponsors

Maruyama Michihiro
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Inclusion Criteria for Consent Procedure The following conditions (1 to 3) must all be met 1.Age Requirement: Individuals aged 20 years or older at the time of obtaining consent. 2.Diagnosis: Patients diagnosed with gastrointestinal malignant tumors (e.g. esophageal cancer, gastric cancer, colorectal cancer, sarcoma, malignant lymphoma, etc.). 3.Informed Consent: Individuals who, after receiving sufficient explanation regarding participation in this study, fully understand the details and provide written consent of their own free will. Opt-Out Research Subjects Individuals who have not expressed a refusal to participate in this study through the information disclosure documents.

Exclusion criteria

Exclusion criteria: Exclusion Criteria Individuals who meet any of the following conditions: 1.Difficulty Chewing Xylitol Gum: Individuals who find it difficult to chew xylitol-containing gum in their daily lives. 2.Refusal to Participate: Individuals who have explicitly expressed refusal to participate in this study through the information disclosure documents. 3.Other Reasons: Patients deemed unsuitable for participation by the principal investigator or sub-investigator.

Design outcomes

Primary

MeasureTime frame
Correlation Between Oral Findings and Treatment Outcomes in Patients with Gastrointestinal Malignancies Correlation of Sarcopenia and Frailty with Masticatory Ability and Oral Frailty Findings in Patients with Malignant Tumors

Secondary

MeasureTime frame
Relationship with Occlusal Muscles and Muscle Mass

Contacts

Public ContactTenshi Makiyama

Chiba University Hospital

cfaa0080@chiba-u.jp+81-43-226-2109

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026