Cancer cancer,
Conditions
Interventions
Participants will be exposed to either sounds beyond the audible range only or a silent condition.
music therapy
extraaudible range, music therapy
Sponsors
Miura Tomofumi
Eligibility
Inclusion criteria
Inclusion criteria: Eligible participants must meet the following criteria: Age: 18 years or older at the time of obtaining consent. Cancer Diagnosis: Diagnosed with cancer either histologically or clinically. Hospitalization: Currently admitted to a palliative care ward. Monitoring Capability: Able to undergo EEG and ECG monitoring. Language: Native Japanese speaker. Delirium Status: Not diagnosed with delirium (negative Confusion Assessment Method, CAM). Consent: Capable of understanding and signing the informed consent document.
Exclusion criteria
Exclusion criteria: Exclusion criteria apply if any of the following conditions are met: CNS Disorders: History of central nervous system conditions, such as cerebral infarction, cerebral hemorrhage, or metastatic brain tumors. Severe Symptoms: Presence of severe physical or psychological symptoms. Hearing Loss: Hearing impairment requiring the use of a hearing aid in daily life. Oral/Mandibular Restrictions: Limited tongue or jaw mobility due to lesions or treatments. Researcher Judgment: Deemed unsuitable for participation by the principal investigator.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Comparison of the change in the proportion of alpha waves in EEG when exposed to sounds beyond the audible range versus a silent condition | — |
Secondary
| Measure | Time frame |
|---|---|
| Comparison of changes in EEG power spectrum and amplitude when exposed to sounds beyond the audible range versus a silent condition. Comparison of changes in EEG power spectrum and amplitude when exposed to natural sounds containing frequencies beyond the audible range versus natural sounds with those frequencies removed. Comparison of changes in autonomic nervous function and heart rate variability analysis based on ECG when: Exposed to sounds beyond the audible range versus a silent condition, and Exposed to natural sounds containing frequencies beyond the audible range versus natural sounds with those frequencies removed. Comparison of changes in the healing scale (total score and subscales) when: Exposed to sounds beyond the audible range versus a silent condition, and Exposed to natural sounds containing frequencies beyond the audible range versus natural sounds with those frequencies removed. Comparison of changes in symptom scales (ESAS-r-J) when: Exposed to sounds beyond the audible range versus a silent condition, and Exposed to natural sounds containing frequencies beyond the audible range versus natural sounds with those frequencies removed. Comparison of PGI-C (Patient Global Impression of Change) when: Exposed to sounds beyond the audible range versus a silent condition, and Exposed to natural sounds containing frequencies beyond the audible range versus natural sounds with those frequencies removed. | — |
Contacts
Public ContactKoshin Katsu
National Cancer Center Hospital East
Outcome results
None listed