childhood cancer, breast cancer
Conditions
Interventions
home-based exercise therapy
Sponsors
Akazawa Hiroshi
Eligibility
Inclusion criteria
Inclusion criteria: 1. Childhood cancer and breast cancer survivors with a history of cancer treatment involving cardiotoxic chemotherapy or hematopoietic stem cell transplantation. 2. Individuals with sufficient physical ability to undergo cardiopulmonary exercise testing and participate in home-based exercise therapy. 3. Individuals who, after receiving a thorough explanation of the study and fully understanding it, have provided written consent of their own free will.
Exclusion criteria
Exclusion criteria: 1. History of cardiovascular disease 2. Active infection 3. History of mental illness 4. Pregnancy or breastfeeding 5. Other cases deemed unsuitable for this study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| peak VO2 | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Cardiac function indicators and lifestyle-related disease markers obtained from routine clinical care such as blood pressure, body weight, lipid metabolism, glucose metabolism, heart failure biomarkers (BNP, NT-proBNP), echocardiogram findings. 2. Health-related quality of life (HR-QOL) scores evaluated by SF-36 3. Additional indicators obtained from CPX and the 6-minute walk test besides peak VO2 4. Changes in body composition analysis results obtained by InBody 5. Adherence rate to home-based exercise therapy | — |
Contacts
Public ContactAkito Shindo
The University of Tokyo Hospital
Outcome results
None listed