A prospective multicenter study of the risk of developing CVD in hemophiliacs

A prospective multicenter study on risk assessment of cardiovascular diseases (CVD) in patients with hemophilia

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-jRCT1030240319

Enrollment

200

Registered

2024-09-05

Start date

2024-09-05

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hemophilia A, Hemophilia B Acute Coronary Syndrome, Cerebral Infarction

Interventions

Performing non-contrast coronary CT imaging, non-contrast head and neck MRI imaging and pulse wave testing

D014057, D008279, D063177

coronary CT, head and neck MRI imaging,

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Congenital hemophilia A or hemophilia B (regardless of severity) Age of the patient must be at least 30 years old Informed consent is required

Exclusion criteria

Exclusion criteria: Acquired coagulation factor deficiency, including acquired hemophilia Congenital coagulation factor deficiency other than hemophilia Under 30 years of age. Unable to give informed consent Women who are pregnant or may become pregnant.

Design outcomes

Primary

Measure	Time frame
Framingham score, a risk score for cardiovascular disease Prevalence of coronary artery calcium score of 101 or higher on coronary CT PVH/DSWMH grade on head and neck MRI	—

Secondary

Measure	Time frame
Prevalence of those who are referred to a cardiologist or neurosurgeon specialist and require initiation of anticoagulation therapy	—

Contacts

Public ContactYushi Chikasawa

Tokyo medical university

yushi_c@tokyo-med.ac.jp+81-9052790786

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026