Sex differences in cerebral autoregulation during postural change from supine to sitting position

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-jRCT1030240183

Enrollment

Registered

2024-06-24

Start date

2024-06-24

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Orthostatic hypotension Hypotension, Orthostatic

Interventions

Postural change from supine to sitting position

D000077708

Postural change, Sitting position

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1.Healthy 2.Regular menstrual cycles(25-38 days)

Exclusion criteria

Exclusion criteria: 1.Any history of cardiovascular, neurological, respiratory, autonomic dysfunction, or severe systemic disease 2.Taking hormone drugs, irregular menstrual cycles(except for 25-38 cycles), and pregnant

Design outcomes

Primary

Measure	Time frame
1.cerebral blood flow velocity in the middle cerebral artery(MCA) 2.Index of dynamic cerebral autoregulation : gain, phase, coherence	—

Secondary

Measure	Time frame
heart rate, mean blood pressure at heart level, mean blood pressure at MCA level, respiratory rate, end-tidal carbon dioxide concentration, percutaneous saturation of arterial oxygen, non-invasively estimated intracranial pressure, non-invasively estimated cerebral perfusion pressure	—

Contacts

Public ContactHanae Ito

Nihon University

itou.hanae@nihon-u.ac.jp+81-3-3972-8111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026