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Development of objective indicators to predict the effects of brief interventions in habitual drinkers

Development of an Objective index to Predict the Effectiveness of a Brief Intervention for Heavy Drinkers : A Study Based on Frontal Lobe Function

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
JPRN
Registry ID
JPRN-jRCT1030240144
Enrollment
60
Registered
2024-06-07
Start date
2024-03-08
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

alcohol use diosrder

Interventions

The study will provide approximately 30 minutes of advice and counseling on drinking behavior (brief intervention). The brief intervention was based on what has been shown to be effective in previous
brief interveintion

Sponsors

sumiyoshi tomiki
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1) Drinks alcohol on three or more days per week, 2) Drinking more than the following amounts Men: 4 or more drinks (2 x 500 ml beer, 2 x 1 g of sake, 2 x 350 ml canned shochu, 1 g of shochu, 4 glasses of wine, 2 double whiskey) per occasion Women: 2 or more drinks per occasion (500 mL beer, 1 gou of sake, 350 ml can of shochu, 0.5 gou of shochu, 2 glasses of wine, 1 double shot of whiskey) 3) Have not been diagnosed as an alcoholic at a treatment facility 4) Age between 20 and 65 years old at the time consent is obtained 5) Understand the purpose and content of this study and are able (competent) to obtain consent to participate in the study.

Exclusion criteria

Exclusion criteria: 1) Patients with a history of severe cerebral organic lesions (with loss of consciousness for more than 10 minutes) or epilepsy, or a history of coexisting or existing epilepsy. 2) A history of or current treatment for a neurodegenerative disease 3) Alcohol withdrawal syndrome with impaired consciousness 4) Dementia or suspected dementia 5) Received support or treatment (health center, mental health center, or hospital) for alcohol problems within 1 year 6) Pregnant 7) identified suicide 8) Other, as deemed inappropriate by the principal investigator

Design outcomes

Primary

MeasureTime frame
P300 amplitude during oddball task

Secondary

MeasureTime frame
TMT score stroop test score DSST score verbal fluency score

Contacts

Public ContactRisa Yamada

National Center of Neurology and Psychiatry

riyamada@ncnp.go.jp+81-42-341-2711

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026