Investigation of the dependence of melanopsin-mediated pupillary response on measurement conditions.

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

JPRN

Registry ID

JPRN-jRCT1030230756

Enrollment

Registered

2024-03-29

Start date

2024-03-29

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy subjects

Interventions

Measurement of post-illumination pupil response (PIPR): Red or blue LED light is presented for one to several tens of seconds to subjects who have adapted to the dark.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) Persons who are between 18 and 60 years of age at the time of consent

Exclusion criteria

Exclusion criteria: 1) Persons with mental illness 2) Those with neurodegenerative diseases 3) Persons with abnormal color vision 4) Persons with a fear of the dark 5) Other subjects deemed inappropriate by the principal investigator.

Design outcomes

Primary

Measure	Time frame
Dependence of PIPR measurement results on optical stimulus presentation time and optical system	—

Secondary

Measure	Time frame
Exploling for individual factors (age, gender, pupil sutra, chronotype, mood state, etc.) that contribute to PIPR measurement results and dependence on measurement conditions	—

Contacts

Public ContactTaisuke Eto

National Center of Neurology and Psychiatry

eto@ncnp.go.jp+81-42-346-2071

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026