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Retrospective analysis of patient flow in NSCLC with delayed detection of druggable mutation using C-CAT database

Retrospective analysis of patient flow in NSCLC with delayed detection of druggable mutation using C-CAT database - C-CAT data base study in NSCLC patients

Status
Recruiting
Phases
Unknown
Study type
Unknown
Source
JPRN
Registry ID
JPRN-jRCT1030230246
Enrollment
1314
Registered
2023-07-20
Start date
2023-07-20
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

NSCLC NSCLC, C-CAT, driver gene

Interventions

None listed

Sponsors

Yokochi Yuya
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Adult (aged 15 years or more) patients with histologically or cytologically confirmed NSCLC

Exclusion criteria

Exclusion criteria: 1. Patients who have already been confirmed to have a drug-treatable mutation/translocation by the end of standard therapy 2. Patients who received targeted therapy against driver genes before finishing standard therapy

Design outcomes

Primary

MeasureTime frame
Among patients with NSCLC diagnosed with wild type (WT) who have completed (or are expected to complete) standard therapy and who underwent comprehensive genomic profiling (CGP) testing, the proportion of patients diagnosed with a drug-treatable mutation by CGP testing ratio Among patients with NSCLC diagnosed with WT who have completed (or are expected to complete) standard therapy and who underwent comprehensive genomic profiling (CGP) testing, the proportion of patients diagnosed with a drug-treatable mutation by CGP testing , percentage by year

Secondary

MeasureTime frame
Describe the characteristics of NSCLC patients with delayed detection of drug-treatable genetic mutations Describe the degree of delay in NSCLC patients with delayed detection of drug-treatable genetic mutations Describe treatment patterns for NSCLC patients with delayed detection of drug-treatable genetic mutations Describe the frequency of delayed detection of drug-treatable genetic mutations by site type Patient baseline characteristics (gender, age, family history, etc.) Time from start of first-line therapy to detection of a drug-treatable mutation Treatment patterns for NSCLC patients with drug-treatable mutations Number and proportion of regimens in each line of treatment Duration of each line of therapy Percentage of patients diagnosed with a drug-treatable mutation by CGP testing, by facility type (size, academic/community, etc.)

Contacts

Public ContactDirect Novartis

Novartis Pharma K.K.

imi.medica.mee.csmap@novartis.com+81-120003293

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026