Spinocerebellar degeneration, multiple system atrophy, Parkinson's disease
Conditions
Interventions
Heart rate variability and heart rate turbulence by 24-hour Holter electrocardiography
The data is recorded by "Long-time ECG recorder RAC-5103" manufactured by Nihon Kohden, and analyzed by "Analys
Sponsors
Ikeda Yoshio
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Patients 18 years of age or older, regardless of gender. (2) Patients who meet one of the following criteria are eligible 1. patients with spinocerebellar degeneration who meet the diagnostic criteria of Definite or Probable according to the Intractable Disease Information Center of the Ministry of Health, Labour and Welfare of Japan 2. patients with multiple system atrophy who meet the diagnostic criteria according to the 2nd Consensus Criteria (2008) 3. patients with Parkinson's disease who meet the diagnostic criteria of the Intractable Disease Information Center of the Ministry of Health, Labour and Welfare 4. patients with progressive supranuclear palsy who meet the diagnostic criteria of the Intractable Disease Information Center of the Ministry of Health, Labour and Welfare Patients with basal ganglia degeneration who meet the diagnostic criteria of the Intractable Disease Information Center of the Ministry of Health, Labour and Welfare (MHLW) 6. patients with amyotrophic lateral sclerosis who meet the criteria for clinically probable-laboratory-supported ALS or higher on the El Escorial revised Airlie House diagnostic criteria 7. patients with neuronal inclusion body disease who meet the diagnostic criteria proposed by Chen et al. in 2020 8. patients with diseases other than 1-7 who are hospitalized in the Department of Neurology of the hospital 3) Patients without indwelling urinary catheter 4) Patients who can walk longer than 10 m with firm assistance when gait analysis is performed. 5) Patients who have given written consent to participate in this study.
Exclusion criteria
Exclusion criteria: (1) Patients with a history of intracranial or spinal cord diseases other than the target diseases (2) Patients with atrial fibrillation (3) Other patients who are judged by the physician to be ineligible
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Evaluation of heart rate variability/heart rate disturbance by 24-hour Holter ECG Measurement of residual urine volume Gait analysis | — |
Secondary
| Measure | Time frame |
|---|---|
| CV-RR by RR interval ECG Questionnaire on urination Blood tests Cognitive function tests (MMSE, FAB, MOCA-J) Shellong test Head MRI SARA, ICARS, UMSARS, UPDRS, PSPRS-J, ALSFRS-R, Limb Norris scale, Norris Bulbar scale | — |
Contacts
Public ContactMasayuki Sato
Gunma University Graduate School of Medicine
Outcome results
None listed