Esophageal achalasia, GERD
Conditions
Interventions
Insertion of an normal endoscope and a ultrathin endoscope into the same patient to measure EPSIS
EPSIS, ultrathin endoscope
Sponsors
Inoue Haruhiro
Eligibility
Inclusion criteria
Inclusion criteria: 1) Prospective study part: Patients with suspected LES dysfunction attending the Digestive Disease Center of Showa University Koto Toyosu Hospital who undergo esophageal endoscopy, barium angiography, or 24-hour pH test in addition to upper gastrointestinal endoscopy. Retrospective study part: From December 5, 2020, until this study is approved by the Ethics Committee and the permission to conduct the study is obtained from the head of the implementing medical institution, patient information from the existing EPSIS study (approval number: UMIN000042661) that is applicable to this study will be used. (2) Patients who are 20 years of age or older at the time of obtaining consent. (3) Patients who have given their written consent to participate in this study.
Exclusion criteria
Exclusion criteria: Patients deemed ineligible at the discretion of the study physician
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To measure the pressure waveform of EPSIS by oral and nasal endoscopy and to study the correlation between EPSIS values by oral and nasal endoscopy. | — |
Secondary
| Measure | Time frame |
|---|---|
| We will verify the usefulness of EPSIS by comparing the correlation between EPSIS pressure waveforms and subjective symptoms and disease severity, as well as the results of various tests (blood tests, pH monitoring, esophageal manometry, barium angiography, upper gastrointestinal endoscopy, etc.) performed on each subject. We will also measure the pressure waveform of EPSIS during gastric inversion and progressive insufflation, and compare the results with those of oral and nasal endoscopy, respectively. | — |
Contacts
Public ContactHitoshi Tanaka
Showa University Koto Toyosu Hospital
Outcome results
None listed