Feasibility of cognitive processing therapy for PTSD patients with drinking problems.

Feasibility of cognitive processing therapy for posttraumatic stress disorder co-occurring with alcohol use disorder.

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-jRCT1030210374

Enrollment

Registered

2021-10-13

Start date

2021-10-13

Completion date

Unknown

Last updated

2025-07-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Posttraumatic Stress Disorder, Alcohol use disorder Posttraumatic Stress Disorder, Alcohol use disorder

Interventions

Cognitive processing therapy is a psychotherapy for PTSD (Resick et al., 2014). Twelve to sixteen weekly sessions (50 minutes for each) will be conducted during the intervention period of 16 weeks.

D015928

cognitive processing therapy

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) DSM-5 diagnosis of Posttraumatic Stress Disorder assessed by CAPS-5 2) Alcohol use disorder at baseline assessed by M.I.N.I.7.0.0 3) Ages 20 years or older, and 70 years or younger at baseline 4) Subjects who give full consent in the participation of the study

Exclusion criteria

Exclusion criteria: 1) No current manic episode or current psychotic disorders at baseline assessed by M.I.N.I.7.0.0 2) No serious suicidal ideation at baseline assessed by M.I.N.I.7.0.0 3) No severe or unstable physical disorders or major cognitive deficits at baseline 4) No alcohol withdrawal symptoms (such as hallucinations, convulsions, and tremors) that require any urgent treatments 5) Not in need of inpatient care 6) No structured psychotherapy at baseline 7) Other relevant reason decided by the investigators

Design outcomes

Primary

Measure	Time frame
Efficacy: Posttraumatic stress symptoms assessed by PTSD Check List for DSM 5 (PCL-5) at 17 week	—

Secondary

Measure	Time frame
Efficacy: 1) Degree of problem drinking (Alcohol Use Disorders Identification Test Consumption; AUDIT-C) 2) Craving for drinkingl (VAS) 3) Severity of subjective depressive Symptoms (Patient Health Questionnaire 9; PHQ -9) 4) Suicidal ideation (Suicidal Ideation Attributes Scale; SIDAS) Feasibility: 1) Severe adverse events	—

Contacts

Public ContactYuriko Takagishi

Surugadai University

takagishi.yuriko@surugadai.ac.jp+81-42-972-1111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Feb 4, 2026