Serotype Distribution and Antimicrobial Susceptibility of Streptococcus pneumoniae Associated with Invasive Pneumococcal Disease among Children in Japan

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-jRCT1030210333

Enrollment

200

Registered

2021-09-22

Start date

2021-11-26

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Invasive Pneumococcal Disease

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Patient age is between 2 months and17 years 2. Patient has S. pneumoniae positive culture from normally sterile sites (i.e., blood or cerebrospinal, synovial, pleural or pericardial fluid or bone) 3. Parents/legally acceptable representatives (LAR) is willing and able to give informed consent for participation in the study

Exclusion criteria

Exclusion criteria: 1. Patient has S. pneumoniae positive ear discharge culture related to acute otitis media without bacteremia or S. pneumoniae positive cerebrospinal fluid 2. Patient has S. pneumoniae positive sputum culture related to pneumococcal pneumonia without bacteremia or S. pneumoniae positive cerebrospinal fluid 3. Patient has S. pneumoniae positive culture obtained from the nasopharynx without bacteremia or S. pneumoniae positive cerebrospinal fluid

Design outcomes

Primary

Measure	Time frame
Count and percentage of pneumococcal serotypes detected in pediatric IPD patients and the summary of IPD cases	—

Secondary

Measure	Time frame
Productivity loss among parents/caregivers of patients diagnosed with IPD	—

Contacts

Public ContactNao Shimoda

CMIC Co., Ltd.

IPD_RS@cmic.co.jp+81-120-744-032

Outcome results