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Multi-institutional clinical study to verify the efficacy and safety of wearing custom-made compression elastic garment for 6 months in cases of Klippel-Trenaunay syndrome with venous malformation

Multi-institutional clinical study to verify the efficacy and safety of wearing custom-made compression elastic garment for 6 months in cases of Klippel-Trenaunay syndrome with venous malformation

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
JPRN
Registry ID
JPRN-jRCT1030210271
Enrollment
20
Registered
2021-08-24
Start date
2021-08-24
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Klippel Trenaunay Weber syndrome

Interventions

Compression therapy by wearing the custom-made elastic garment for 26 weeks, Stopping the ongoing compression therapy using the elastic bandage or the srtandard garment 3 days before measuring the aff

Sponsors

Yuzuriha Shunsuke
Lead Sponsor
The Health, Labor and Welfare Sciences Research Grants (Research on Measures for Intractable Diseases), Research Committee for Intractable Vascular Anomalies (a representative: Sadanori Akita)
Collaborator

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patients who have some typess of vascular malformations including venous malformation on the unilateral lower leg, are dagnosed as Klippel-Trenaunay syndorome, and can walk independently.

Exclusion criteria

Exclusion criteria: Patients who have bilateral lesions, those who had treated by sclerotherpy or surgery in 12 weeks, those who have allergic reactions to materials of the elastic garment, those who are continuously administered diuretic medicine to, and those who suffered from heart failure within 1 year.

Design outcomes

Primary

MeasureTime frame
Comparison value of the circumference of the affected lower leg with respect to the circumference of the non-affected lower leg.

Secondary

MeasureTime frame
Measuring water content of the affected leg using the bioelectrical impedance analysis. Pain evaluation using the 5-point visual analogue scale. The modified Rankin Scale based on activities of daily living. Blood pressure and heart pulsation values. Elasytic strength of the garment material.

Contacts

Public ContactShunsuke Yuzuriha

Shinshu University

yuzuriha@shinshu-u.ac.jp+81-263-37-2833

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026