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Komagome PROGRES Project

Study of a genome-based precision medicine for malignant lymphomas and solid tumors, and the verification of its clinical usefulness.

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
JPRN
Registry ID
JPRN-jRCT1030190169
Enrollment
120
Registered
2019-12-24
Start date
2019-12-24
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Malignant lymphomas, Solid tumors Malignant lymphoma

Interventions

none

Sponsors

Shimoyama Tatsu
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Subject must satisfy the inclusion criteria (4.3.2) among the subjected patients (4.3.1) and do not meet any of the exclusion criteria. 4.3.1 Subjected patient Patients with malignant lymphoma or solid cancer* treated in Tokyo Metropolitan Komagome Hospital (* stomach cancer, colon cancer, pancreatic cancer, gallbladder cancer, bile duct cancer, head and neck cancer, etc.) 4.3.2 Inclusion criteria Subject is 20 years or older of age at the time of obtaining consent. Histologically or cytologically proven malignant tumor. Subject must understand and voluntarily sign the informed consent form after receiving sufficient explanation for participation in this study

Exclusion criteria

Exclusion criteria: Subject who has complicated psychiatric illness or symptoms that interfere with daily life and is considered difficult to participate in the study Subject who has any medical condition that would prevent the subject from participating in the study based on investigator's judgment.

Design outcomes

Primary

MeasureTime frame
The rate at which any genetic abnormality is detected Percentage of each gene abnormality

Secondary

MeasureTime frame
Number of somatic cell line mutations and mutation rate in exons Positive rate of biomarkers (things that are directly related to therapeutic drugs/treatment methods) Treatment options after oncogene panel testing Objective response rate (including correlation between biomarker and therapeutic response) Disease control rate Overall survival and progression free survival Number of germline mutations suspected and confirmed by Sanger sequencing

Contacts

Public ContactTatsu Shimoyama

Tokyo Metropolitan Cancer and Infectious Diseases Center Komagome Hospital

tshimoya@cick.jp+81-3-3823-2101

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026