Healthy adults (no particular disease) Healthy Volunteers
Conditions
Interventions
1. Optimism intervention group: participants were presented with highly likely positive events, such as "enjoying a delicious dinner with a close friend," and highly unlikely negative events, such as
D001943
Behavioral Theapy
Sponsors
SUGIURA Motoaki
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1.Age: 18-40 years old (when registering) 2.Right-handed 3.Any gender 4.Individuals who have given written consent to participate in the study
Exclusion criteria
Exclusion criteria: Task 1: Behavioral Experiment on the Effects of Optimism Induction on Experimental Pain 1. Individuals experiencing pain from injury or other causes at the time of recruitment. 2. Individuals with allergies to capsaicin. 3. Individuals who are pregnant or may be pregnant. 4. Individuals using analgesics or drugs affecting the central nervous system. 5. Individuals with neurological or psychiatric disorders (including a history of these). 6. Individuals with skin disorders (such as atopic dermatitis) that may cause inflammation or irritation from capsaicin cream application.Task 2: fMRI Experiment on the Effects of Optimism Induction on Experimental Pain and Brain Activity 1. Individuals experiencing pain from injury or other causes at the time of recruitment. 2. Individuals with allergies to capsaicin. 3. Individuals who are pregnant or may be pregnant. 4. Individuals using analgesics or drugs affecting the central nervous system. 5. Individuals with neurological or psychiatric disorders (including a history of these). 6. Individuals who meet MRI contraindications (to be confirmed using the MRI pre-screening checklist). 7. Individuals with a tendency toward claustrophobia. 8. Individuals who participated in Task 1: Behavioral Experiment on the Effects of Optimism Induction on Experimental Pain. 9. Individuals with skin disorders (such as atopic dermatitis) that may cause inflammation or irritation from capsaicin cream application.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain intensity (capsaicin-induced): VAS visual analogue scale score | — |
Secondary
| Measure | Time frame |
|---|---|
| Task 1: Behavioral experiment on the effect of optimism induction on experimental pain 1. Optimism scale (LOT-R optimism) 2. Pain catastrophizing scale (Pain Catastrophizing Scale (PCS) Pain catastrophizing scale) 3. Personality trait scale (Big Five scale Japanese abbreviated version) Task 2: fMRI experiment on the effect of optimism on experimental pain and brain activity 1. Optimism scale (LOT-R optimism) 2. Changes in brain activity (by fMRI scan) 3. Pain catastrophizing scale (Pain Catastrophizing Scale (PCS) Pain catastrophizing scale) Personality trait scale (Big Five scale Japanese abbreviated version) | — |
Contacts
Public ContactXIAOQIAN CHANG
980-857
Outcome results
None listed