The effect of Selexipag on coagulation and fibrinolysis

The effect of Selexipag on coagulation and fibrinolysis - Selegxipag on coagulation and fibrinolysis

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-jRCT1021240025

Enrollment

Registered

2024-09-20

Start date

2024-09-09

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic thromboembolic pulmonary hypetension pulmonary hypertension

Interventions

nothing

Eligibility

Inclusion criteria

Inclusion criteria: The patinet undertake the right heart catheterization to diagnose or treat chronic thromboembolic pulmonary hypertension

Exclusion criteria

Exclusion criteria: Patients who are judged by the attending physician to be unsuitable for this study

Design outcomes

Primary

Measure	Time frame
Below assessment are performed before and after the treatment with Seloxipag. Plasma clot lysis time, The score of coagulation or fibrinolysis as below: Plasminogen, PAI-1, Thrombin-Antithrombin, Thrombomodulin,TAFI	—

Secondary

Measure	Time frame
cytokines chemokines: IL-1alpha, IL-1beta, IL-2, IL-3, IL-4, IL-5, IL-6, IL-7, IL-8, IL-9, IL-10, IL-12, IL-13, IL15, IL-16, IL17, IL-18, IL-23, IL-1ra, IL-2Ralpha, Eotaxin, G-CSF, GM-CSF, IFN-ganma, KC, MCP-1, MIP-alpha, MIP-beta, TNF-alpha, TNF-beta, RANTES, FGF-basic, IP-10, GROa, HGF, IFN-alpha2, MCP-3, MIF, LIF, M-CSF, MIG, MIP-2, PDGF-BB, VEGF, TRAIL, CTACK, SDF-1aplha, b-NGF, SCF, SCGF-beta, P-selectin, PAC-1 Platelet function	—

Measure

Time frame

cytokines chemokines: IL-1alpha, IL-1beta, IL-2, IL-3, IL-4, IL-5, IL-6, IL-7, IL-8, IL-9, IL-10, IL-12, IL-13, IL15, IL-16, IL17, IL-18, IL-23, IL-1ra, IL-2Ralpha, Eotaxin, G-CSF, GM-CSF, IFN-ganma, KC, MCP-1, MIP-alpha, MIP-beta, TNF-alpha, TNF-beta, RANTES, FGF-basic, IP-10, GROa, HGF, IFN-alpha2, MCP-3, MIF, LIF, M-CSF, MIG, MIP-2, PDGF-BB, VEGF, TRAIL, CTACK, SDF-1aplha, b-NGF, SCF, SCGF-beta, P-selectin, PAC-1 Platelet function

—

Contacts

Public ContactSatoh Taijyu

Tohoku University Graduate School of Medicine

s-taiju@cardio.med.tohoku.ac.jp+81-227177153

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026