Safety of dexamethasone suppression test for adrenal masses

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-jRCT1021230051

Enrollment

Registered

2024-01-12

Start date

2024-01-12

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

adrenal mass adrenal mass

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients admitted to our hospital for the examination of adrenal masses and need to rule out cortisol excess production

Exclusion criteria

Exclusion criteria: Patients on oral steroid therapy.

Design outcomes

Primary

Measure	Time frame
After drawing blood at rest at 23:00 midnight, patients take 1 to 2 dexamethasone 0.5 mg tablets. Fasting resting blood samples will be taken at 6-7 a.m. the next morning, and blood pressure on the morning of dexamethasone administration will be compared with that on the morning of the next day. In addition to adrenocorticotropic hormone and cortisol as originally evaluated in the 1 mg dexamethasone study, blood counts and biochemical tests (blood catecholamine, AST, ALT, ALP, gamma GTP, NT-proBNP, CPK, BUN, Cre, Na, K, Cl) will be taken.	—

Measure

Time frame

After drawing blood at rest at 23:00 midnight, patients take 1 to 2 dexamethasone 0.5 mg tablets. Fasting resting blood samples will be taken at 6-7 a.m. the next morning, and blood pressure on the morning of dexamethasone administration will be compared with that on the morning of the next day. In addition to adrenocorticotropic hormone and cortisol as originally evaluated in the 1 mg dexamethasone study, blood counts and biochemical tests (blood catecholamine, AST, ALT, ALP, gamma GTP, NT-proBNP, CPK, BUN, Cre, Na, K, Cl) will be taken.

—

Contacts

Public ContactShingo Murasawa

Hirosaki University Graduate School of Medicine

murashin@hirosaki-u.ac.jp+81-172-39-5062

Outcome results