A study examining the relationship between delirium and the status of eating and drinking by mouth after cardiac and thoracic vascular surgery

Association between postoperative cognitive dysfunction and persistent dysphagia after general anesthesia for cardiac and thoracic vascular surgery: a retrospective cohort study

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-jRCT1020260007

Enrollment

700

Registered

2026-05-15

Start date

2026-05-15

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ischemic, valvular, and aortic diseases, and other heart diseases Myocardial Ischemia, Acute Coronary Syndrome, Myocardial Infarction, Angina Pectoris, Heart Valve Diseases, Aortic Dissection, Aortic Aneurysm, Cardiomyopathies, Endocarditis, Heart Diseases

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) Adult patients who underwent open cardiac or thoracic aortic surgery under general anesthesia at Hirosaki University Hospital between September 1, 2021 and August 31, 2025, and who were admitted to the ICU postoperatively. 2) Patients who can be identified from our institutional data registered in the Japanese Intensive care PAtient Database (JIPAD) as having undergone coronary artery bypass grafting, coronary artery bypass grafting plus valve surgery, valve surgery, surgery for acute aortic dissection, surgery for ruptured aortic aneurysm, or elective surgery for aortic aneurysm.

Exclusion criteria

Exclusion criteria: 1) Patients younger than 18 years of age. 2) Patients who underwent surgery without thoracotomy. 3) Patients with preoperative dysphagia. 4) Patients with a history of intracerebral hemorrhage, cerebral infarction, dementia, or intellectual disability. 5) Patients with a history of progressive neuromuscular disease. 6) Patients who required reintubation or surgical re-exploration for postoperative bleeding or pericardial tamponade. 7) Patients whose primary outcome could not be evaluated. 8) Patients who died during hospitalization.

Design outcomes

Primary

Measure	Time frame
Functional Oral Intake Scale (FOIS) level at day 14 after ICU admission	—

Secondary

Measure	Time frame
1) Highest Intensive Care Delirium Screening Checklist (ICDSC) score recorded within 7 days after ICU admission 2) Presence of an ICDSC score of 3 or higher within 7 days after ICU admission 3) Patient characteristics, including age, sex, and body mass index (BMI) 4) Acute Physiology and Chronic Health Evaluation II (APACHE II) score 5) Surgical category 6) Presence of chronic comorbidities 7) Use of intra-aortic balloon pumping and extracorporeal membrane oxygenation during the ICU stay 8) Tracheostomy during the ICU stay 9) ICU length of stay and hospital length of stay 10) Total intubation duration	—

Measure

Time frame

1) Highest Intensive Care Delirium Screening Checklist (ICDSC) score recorded within 7 days after ICU admission 2) Presence of an ICDSC score of 3 or higher within 7 days after ICU admission 3) Patient characteristics, including age, sex, and body mass index (BMI) 4) Acute Physiology and Chronic Health Evaluation II (APACHE II) score 5) Surgical category 6) Presence of chronic comorbidities 7) Use of intra-aortic balloon pumping and extracorporeal membrane oxygenation during the ICU stay 8) Tracheostomy during the ICU stay 9) ICU length of stay and hospital length of stay 10) Total intubation duration

—

Contacts

Public ContactIppei Tamura

Hirosaki University Graduate School of Medicine

h24gm208@hirosaki-u.ac.jp+81-172-39-5318

Outcome results