Research on radiotherapy in elderly patients with bladder cancer.

Multi-institutional prospective study of hypofractionated radiotherapy in elderly patients with muscle-invasive bladder cancer.

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-jRCT1020230038

Enrollment

Registered

2023-11-11

Start date

2023-11-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bladder cancer Bladder cancer, Eldery, Radiotherapy

Interventions

None listed

Eligibility

Inclusion criteria

Inclusion criteria: (1) Bladder cancer diagnosed as urothelial carcinoma (2) cT2-4aN0M0 (UICC 8th edition) on imaging within 56 days prior to registration (3) Eastern Cooperative Oncology Group (ECOG) PS 0-2 (4) Not scheduled to receive concomitant chemotherapy for bladder cancer (any previous therapy) (5) Plans to receive radiotherapy that meets the prescribed dose fractions and dose constraints (6) No history of radiotherapy to the pelvis

Exclusion criteria

Exclusion criteria: (1) If the patient has serious physical symptoms that make it difficult for the patient to cooperate in the study (2) If the patient has serious psychiatric symptoms (severe cognitive dysfunction, severe depression) that make it difficult to cooperate in the study (3) If the researcher otherwise deems it inappropriate for the patient to participate in the study.

Design outcomes

Primary

Measure	Time frame
event-free survival	—

Secondary

Measure	Time frame
Overall survival (3-year overall survival rate) Progression pattern Completion of treatment (%) Acute and late adverse event rate Quality of life assessment (FACT-BL, OABSS) G8. Comparison of endpoints between treatments where possible	—

Contacts

Public ContactKoyo Kikuchi

Iwate Medical University Hospital

kikuchi@iwate-med.ac.jp+81-19-613-7111

Outcome results