Monitoring Recurrence of Individual tumor by serial Observation of Known gene Alterations

Monitoring Recurrence of Individual tumor by serial Observation of Known gene Alterations - MORIOKA study

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-jRCT1020190017

Enrollment

200

Registered

2020-01-24

Start date

2019-07-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pan-cancer (approximately 20 types of origins) Pan-cancer, malignancy

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: >Diagnosis of malignancy. Histologic diagnosis is preferred but not mandatory. >Intention to treat for volume reduction or growth suppression of the tumor. Cases receive secondary treatment are eligible. Cases with nodes or organ metastasis are accepted. >Estimated life expectancy is longer than 180 days. >Stages estimated having approximately 30% recurrence rate. >Pre-treatment blood sample is available.

Exclusion criteria

Exclusion criteria: >Treatment has initiated without pre-treatment blood sample. >Pregnancy. >Periodical survey is difficult due to location or financial reasons. >Any other ineligible reasons.

Design outcomes

Primary

Measure	Time frame
Progression-free survival	—

Secondary

Measure	Time frame
>Proportion of cases whose ctDNA changes according to tumor burden >Proportion of cases whose ctDNA changes while tumor burden changes	—

Countries

Japan, Republic of Korea

Contacts

Public ContactSatoshi Nishizuka

Iwate Medical University

snishizu@iwate-med.ac.jp+81-16-651-5111

Outcome results