Perioperative serum SIRT6 and flailty

Changes in perioperative serum SIRT6 and patient outcomes in frail

Status

Recruiting

Phases

Phase 2

Study type

Observational

Source

JPRN

Registry ID

JPRN-jRCT1012240016

Enrollment

Registered

2024-06-18

Start date

2023-12-18

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Frailty

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients 65 years of age or older scheduled for abdominal open surgery

Exclusion criteria

Exclusion criteria: Progressive degenerative disease, Mini-Mental State Examination-Thai version (MMST10) score less than 23, Severe audiovisual impairment, Severe physical disability

Design outcomes

Primary

Measure	Time frame
Seruma SIRT6 concentration	—

Secondary

Measure	Time frame
Sirt6 deacetylase activities, postoperative delirium onset, cognitive function, renal impairment, hepatic impairment, oxygen demand, patient outcome, prognosis, ventilator rate, blood purification rate	—

Contacts

Public ContactSoichi Tanak

Sapporo Medical University School of Medicine

soichi.t321@gmail.com+81-116112111

Outcome results