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Investigate the benefit in modifying the treatment plan during a course of proton therapy in pancreatic and liver cancer.

Prospective Clinical Trial to Evaluate the Usefulness of Adaptive Proton Therapy in Pancreatic and Liver Cancer

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-jRCT1012230030
Enrollment
40
Registered
2023-08-08
Start date
2023-08-08
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pnacreatic cancer Liver cancer pancreatic cancer, liver cancer

Interventions

Adaptive proton therapy
D046650

Sponsors

Uchinami Yusuke
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patients who are 20 years of age or older at the time of obtaining consent ECOG performance status is 0 Patients with pathologically confirmed malignancy or clinically diagnosed malignancy No evidence of distant metastasis Judged to be appropriate for proton therapy by multidisciplinary tumor board

Exclusion criteria

Exclusion criteria: In patients with pacreatic cancer, previous treatment of radiotherapy or surgery Pregnant women or those who are breastfeeding Judged by the principal investigator to be inappropriate

Design outcomes

Primary

MeasureTime frame
Number of replanning during proton therapy based on the planning CT images

Secondary

MeasureTime frame
Rate of adverse events occurring up to 6 months post-treatment Number of times tumor dose constraint could not be achieved at the mid-treatment evaluation CT Number of times gastrointestinal dose constraints were not achieved at mid-treatment evaluation CT

Contacts

Public ContactYusuke Uchinami

Department of Radiation Oncology, Hokkaido University Faculty of Medicine and Graduate School of Medicine

uchinamiy@gmail.com+81-11-706-5977

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026