Efficacy of Acumen HPI system

Efficacy of Acumen HPI system to reduce intraoperative hypotension

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-jRCT1012220033

Enrollment

Registered

2022-12-29

Start date

2023-02-13

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Non-cardiac surgery

Interventions

-Hemodynamic monitoring with arterial line- Goal directed therapy is performed with Acumen HPI system (Edwards Life Science, 30400BZX00002000) during surgery. -Administration of hemodynamic drugs bas

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: equal to or older than 45 years old Patients who receive non-cardiac surgery under general anesthesia Patients who are scheduled to be managed with arterial line

Exclusion criteria

Exclusion criteria: Emergent surgery Vascular surgery, hepatic sugery, neurosurgery Thoracic surgery, surgery with prone position, severe valvular disease, arrhythmia, intracardiac shunt, chronic hemodyalisis Other patients who are considered inappropriate for the study by the attending anesthesiologists

Design outcomes

Primary

Measure	Time frame
Intraoperative time weighted average (TWA) (mean arterial pressure < 65 mmHg)	—

Secondary

Measure	Time frame
Incidence of hypotension, total number of hypotensive events, average duration of each hypotensibe event, total duration of hypotension, mean MAP under 65 mmHg, area under 65 mmHg for MAP, number of patients that experience an event under 50 mmHg, patients background, anesthetic and surgical factors, dose of hemodynamic drugs, volume of infusion and transfusion, hemodynamic parameters, BGA, admission days, 30-day mortality	—

Measure

Time frame

Incidence of hypotension, total number of hypotensive events, average duration of each hypotensibe event, total duration of hypotension, mean MAP under 65 mmHg, area under 65 mmHg for MAP, number of patients that experience an event under 50 mmHg, patients background, anesthetic and surgical factors, dose of hemodynamic drugs, volume of infusion and transfusion, hemodynamic parameters, BGA, admission days, 30-day mortality

—

Contacts

Public ContactYusuke Yoshikawa

Sapporo Medical University

y.yoshikawa@sapmed.ac.jp+81-11-688-9663

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026