Effects of sevoflurane combination administration with total intravenous anesthesia using Propofol on the stimulus Intensity and threshold of motor evoked potentials.

Effects of inhaled anesthetic administration during total intravenous anesthesia on motor evoked potential stimulus intensity and threshold. - total intravenous anesthesia: TIVA, motor evoked potential: MEP

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-jRCT1011240024

Enrollment

Registered

2024-07-09

Start date

2024-07-09

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Brain neoplasm Brain tumor

Interventions

General anesthesia is performed using sevoflurane combination with propofol. Propofol will be used as the control group and the combination of 0.2 MAC and 0.5 MAC of sevoflurane will be used as the in

D000077149

Inhaled Anesthetics

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients who undergo neurosurgery using motor evoked potential monitoring. Patients whose age more than 20 yrs

Exclusion criteria

Exclusion criteria: Patients who motor evoked potential monitoring can not be performed appropriately.

Design outcomes

Primary

Measure	Time frame
Propofol, sevoflurane 0.2 MAC and 0.5 MAC on suprathreshold stimulus intensity.	—

Secondary

Measure	Time frame
Percentage of same amplitude elicited Threshold Latency of MEP waveform Hemodynamic state including blood pressure and heart rate Depth of sedation evaluated by bistral index value	—

Contacts

Public ContactTomohiro Chaki

Sapporo Medical University School of Medicine Hospital

chakitomohiro0728@yahoo.co.jp+81-90-7051-8560

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026