Effect of low concentration of sevoflurane on MEP

Effect of inhaled anesthetic mixture for total intravenous anesthesia on motor evoked potential: A cross over study

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-jRCT1011220040

Enrollment

Registered

2023-02-28

Start date

2023-02-28

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Brain tumor, cerebrovascular disorder Brain tumor, cerebrovascular disorder

Interventions

After placement of MEP sensor, 0.2 and 0.5 MAC of sevoflurane inhalation is added to propofol anesthesia for 10 minutes each.

D000769

inhalation anesthetics

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patient who undergo neurosurgery with MEP monitoring under general anesthesia

Exclusion criteria

Exclusion criteria: Patient that MEP monitoring cannot be performed normally

Design outcomes

Primary

Measure	Time frame
Rate of successful MEP monitoring (amplitude > 150 mcV)	—

Secondary

Measure	Time frame
Amplitude of MEP wave, latency of MEP wave, hemodynamics (blood pressure, heart rate), BIS value	—

Contacts

Public ContactTomohiro Chaki

Sapporo Medical University School of Medicine Hospital

chakitomohiro0728@yahoo.co.jp+81-11-611-2111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026