Plasma concentration of remimazolam and bispectral index or patient state index

Relationship between plasma concentration of remimazolam and bispectral index or patient state index: a pilot study - Plasma concentration of remimazolam and sedative monitors

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-jRCT1011210071

Enrollment

Registered

2022-03-03

Start date

2022-03-03

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Diseases needed operation under general anesthesia Diseases needed operation under general anesthesia

Interventions

Remimazolam is used for general anesthesia under the sedative monitoring using BIS or Sedline, which are determined by computer randomization

D056805

Consciousness monitors

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients who received general anesthesia Patients who received arterial catheter cannulation for intraoperative management

Exclusion criteria

Exclusion criteria: Patients who have allergy for benzodiazepin drugs Patients who have severe hepatic dysfunction Patients who have severe renal dysfunction Patients who are not suitable for BIS or Sedline sensor Patients who have anemia preoperatively

Design outcomes

Primary

Measure	Time frame
Correlation of plasma concentration of remimazolam - bispectral index and plasma concentration of remimazolam - patient state index	—

Secondary

Measure	Time frame
Time course of plasma concentration of remimazolam Time course of bispectral index Time course of Patient state index	—

Contacts

Public ContactTomohiro Chaki

Sapporo Medical University School of Medicine Hospital

chakitomohiro0728@yahoo.co.jp+81-116112111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026