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Effect of Intraoperative Mechanical Ventilation Settings during General Anesthesia on Surgical Field Visibility in Endoscopic Sinus Surgery: A Randomized Controlled Trial

Effect of Intraoperative Mechanical Ventilation Settings during General Anesthesia on Surgical Field Visibility in Endoscopic Sinus Surgery: A Randomized Controlled Trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-jRCT1010250072
Enrollment
160
Registered
2026-03-25
Start date
2026-03-25
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Eosinophilic chronic rhinosinusitis

Interventions

Mechanical ventilation is performed during general anesthesia with a low tidal volume set at 6 milliliters per kilogram

Sponsors

Sawada Atsushi
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Patients diagnosed with eosinophilic chronic rhinosinusitis who are scheduled to undergo endoscopic sinus surgery 2. Age of 20 years or older 3. American Society of Anesthesiologists Physical Status classification of I to III 4. No restriction on sex 5. Patients who provide written informed consent prior to enrollment

Exclusion criteria

Exclusion criteria: 1. Patients who withdraw consent after providing written informed consent for study participation 2. Patients with chronic obstructive pulmonary disease 3. Patients with a body mass index of 35 kilograms per square meter or higher 4. Patients considered inappropriate for inclusion in this study at the discretion of the attending physician

Design outcomes

Primary

MeasureTime frame
Wormald Surgical Field Grading Scale

Secondary

MeasureTime frame
Assessment of surgical field visibility using the Fromme Boezaart scale and the Modena bleeding score, intraoperative blood loss, postoperative pain, postoperative nausea and vomiting, and the number of analgesic administrations

Contacts

Public ContactAtsushi Sawada

Sapporo Medical University Hospital

atusihon7@gmail.com+81-116112111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026