hypercholesterolemia hypercholesterolemia, dyslipidemia
Conditions
Interventions
None listed
Sponsors
Eiki Jun-ichi
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Patient has at least one documented laboratory test result for LDL-C in the JAMDAS database during the index period. 2) Patient is 18 years or older on the index date. 3) Patient is continuously enrolled in the JAMDAS database for one year or more before the index date and has record of visits and/or prescriptions for lipid lowering agents at the same clinic, with an interval of less than 120 days during the one year prior to the index date. 4) Patient meets one or both of the following two criteria: - patient has a record of a dyslipidemia diagnosis on the index date. - patient has a record of more than one prescription for lipid-lowering agent(s) during the one year before the index date.
Exclusion criteria
Exclusion criteria: 1) Patient is pregnant or lactating on the index date. 2) Patient is participating in any other clinical trials on the index date and/or during the one year prior to the index date.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Proportion of patients who achieved/did not achieve the respective LDL-C goals at the index date and their patient background in Groups 1-3 as defined in the guidelines: - Group 1: secondary prevention patients with their LDL-C goal of <70 mg/dL - Group 2: secondary prevention patients with their LDL-C goal of <100 mg/dL - Group 3: primary prevention patients with their LDL-C goal of <100 mg/dL | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Proportion of patients who achieved/did not achieve the respective LDL-C goals on the index date and their patient background in Groups 1-3, stratified by subgroups 2. Change and percent change in LDL-C and other laboratory measurements compared to the index date and the measurement date before the guideline* revision in Groups 1-3 3. Secondary endpoint 2 stratified by combination of LDL-C goal attainment (+/-) and treatment intensification (+/-) 4. To describe the LDL-C distribution (<55, <70, <100 and <120 mg/dL) of patients in groups 1-3 and to describe patient characteristics for each LDL-C distribution 5. To investigate factors that associated with LDL-C goal attainment in groups 1-3 | — |
Contacts
Public ContactJun-ichi Eiki
MSD K.K
Outcome results
None listed