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Elucidation of Interhemispheric Interaction Mechanisms Using Somatosensory Evoked Potential Testing

Somatosensory Evoked Potential Testing: Validation of the Alternating Left-Right Stimulation Method: The Time Limit for Modulating Contralateral Hemispheric Function via Peripheral Sensory Nerve Electrical Stimulation - Somatosensory Evoked Potential Testing: Validation of the Alternating Left-Right Stimulation Method: The Time Limit for Modulating Contralateral Hemispheric Function via Peripheral Sensory Nerve Electrical Stimulation

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000062062
Enrollment
15
Registered
2026-06-26
Start date
2026-06-01
Completion date
Unknown
Last updated
2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy adult

Interventions

Although this is actually a single-blind randomized trial in which the antecedent stimulus is varied randomly for each subject, data entry is not possible due to a system bug. The following procedu
) Left only, (B) Simultaneous, (C) ISI = 20 ms, (D) 50 ms, (E) 100 ms, (F) 150 ms, (G) 250 ms (alternating left and right) Additional conditions for lower limbs only: 4 conditions (B&#39
) 10 ms, (B&#39
) 15 ms, (C&#39
) 25 ms, (C&#39
) 30 ms Total: 16 conditions (upper and lower limbs) + 4 conditions (lower limbs only) = 20 conditions 9-5. Stimulation parameters Median nerve: 10 mA or less (intensity causing slight thumb

Sponsors

Kyorin University School of Medicine
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Healthy adults aged 18-50 2. Right-handed (LQ equal or more than 40 on the Edinburgh Handedness Inventory) 3. Individuals capable of voluntarily consenting to participate in the study 4. Individuals with no history of neurological abnormalities

Exclusion criteria

Exclusion criteria: History of central nervous system disorders or peripheral neuropathy Metal plates implanted at the stimulation site Implanted medical devices such as pacemakers Use of medications affecting the nervous system Pregnancy or potential pregnancy Skin conditions making it difficult to attach stimulation electrodes

Design outcomes

Primary

MeasureTime frame
SEP Latency UE:P14,N20,P23,N32,P40,N60,N11-N20 LE:P28,N31,P35,N42,P53,N66,N19-P35 Amplitude UE:P14/N20,N20/P23,P23,N32 LE:P28/N31,N31/P35,P35/N42—

Countries

Japan

Contacts

Public ContactSyoichi Tashiro

Kyorin University School of Medicine Department of Rehabilitation Medicine

s-tashiro@ks.kyorin-u.ac.jp+81-422-47-5511

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Sep 19, 2026