Association of Peripheral Blood Mast Cell Progenitors and Their Related Molecules with Clinical Characteristics in Healthy Individuals and Patients with Bronchial Asthma

Association of Peripheral Blood Mast Cell Progenitors and Their Related Molecules with Clinical Characteristics in Healthy Individuals and Patients with Bronchial Asthma - Peripheral Blood Mast Cell Progenitors and Related Molecules in Healthy Individuals and Patients with Bronchial Asthma

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000061957

Enrollment

Registered

2026-06-18

Start date

2026-06-11

Completion date

Unknown

Last updated

2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Asthma

Interventions

Healthy volunteers will be evaluated without any treatment. Patients with mild asthma will be evaluated under their current treatment regimen. Tezepelumab will be administered to patients with severe

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1.Individuals who meet one of the following criteria: Healthy volunteers Patients with mild asthma Patients with severe asthma scheduled to receive biologic therapy 2. Age 20 years or older 3. Provision of written informed consent for participation in the study

Exclusion criteria

Exclusion criteria: Individuals with severe hepatic or renal impairment Individuals who are pregnant, may be pregnant, are breastfeeding, or plan to become pregnant during the study period Individuals deemed unsuitable for participation in the study by the investigator

Design outcomes

Primary

Measure	Time frame
Comparison and Association of Peripheral Blood Mast Cell Progenitors and Their Related Molecules Between Healthy Individuals and Patients with Severe Asthma	—

Secondary

Measure	Time frame
Association of Peripheral Blood Mast Cell Progenitor Counts and Related Molecules with Asthma Severity, Treatment Profiles, Clinical Symptoms, and Pulmonary Function	—

Countries

Japan

Contacts

Public ContactHiroki Tashiro

Saga University Hospital Respiratory Medicine

si3222@cc.saga-u.ac.jp0952342369

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Sep 19, 2026