Non-invasive Evaluation of Urinary Flow Dynamics and Fine Anatomical Structures of the Seminal Tract Using Magnetic Resonance Imaging Techniques

Non-invasive Evaluation of Urinary Flow Dynamics and Fine Anatomical Structures of the Seminal Tract Using Magnetic Resonance Imaging Techniques - MRI-UroSem Study

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000061949

Enrollment

Registered

2026-06-22

Start date

2026-08-01

Completion date

Unknown

Last updated

2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Urolithiasis, hydronephrosis, benign prostatic hyperplasia, lower urinary tract obstruction, and oligozoospermia

Interventions

As part of this observational study, participants will undergo a single non-invasive MRI examination. For urinary tract evaluation, cine magnetic resonance urography (MRU) combined with motion-sensit

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Healthy adult volunteers aged 20 years or older without a history of urolithiasis, benign prostatic hyperplasia, or oligozoospermia. 2. Patients aged 20 years or older with any of the following conditions: history of urolithiasis hydronephrosis lower urinary tract obstruction, including benign prostatic hyperplasia oligozoospermia 3. Participants who understand the study and provide written informed consent.

Exclusion criteria

Exclusion criteria: 1. Contraindications to MRI, including pacemaker implantation or ferromagnetic implants. 2. Pregnancy or possible pregnancy. 3. Difficulty undergoing MRI due to claustrophobia or other reasons. 4. Conditions likely to cause significant MRI artifacts or missing imaging data. 5. Insufficient information required for the primary outcome assessment. 6. Individuals judged inappropriate for participation by the principal investigator or co-investigators.

Design outcomes

Primary

Measure	Time frame
MRI-derived imaging parameters of urinary flow dynamics and seminal tract morphology. Specific parameters include: 1.Frequency and spatial distribution of urinary flow-related signal changes in the renal pelvis. 2.Frequency and spatial distribution of urinary flow-related signal changes in the urinary bladder. 3.Morphological findings of the seminal tract, including the vas deferens and seminal vesicles.	—

Measure

Time frame

MRI-derived imaging parameters of urinary flow dynamics and seminal tract morphology. Specific parameters include: 1.Frequency and spatial distribution of urinary flow-related signal changes in the renal pelvis. 2.Frequency and spatial distribution of urinary flow-related signal changes in the urinary bladder. 3.Morphological findings of the seminal tract, including the vas deferens and seminal vesicles.

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Secondary

Measure	Time frame
1. Association between renal pelvic morphology and stone size or number. 2. Association between renal pelvic morphology and recurrence of urolithiasis. 3. Association between prostatic morphology and severity of lower urinary tract symptoms. 4. Association between prostatic morphology and treatment response in benign prostatic hyperplasia. 5. Association between seminal tract morphology and semen analysis findings.	—

Measure

Time frame

1. Association between renal pelvic morphology and stone size or number. 2. Association between renal pelvic morphology and recurrence of urolithiasis. 3. Association between prostatic morphology and severity of lower urinary tract symptoms. 4. Association between prostatic morphology and treatment response in benign prostatic hyperplasia. 5. Association between seminal tract morphology and semen analysis findings.

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Countries

Japan

Contacts

Public ContactMasaki Kobayashi

Institute of Science Tokyo Urology

koba.uro@tmd.ac.jp03-5803-5295

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Sep 19, 2026