Multi-omics study on host pathophysiology caused by cancer

Multi-omics study on host pathophysiology caused by cancer - Cancer-host multi-omics study

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000061904

Enrollment

Registered

2026-06-14

Start date

2026-01-15

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Primary or metastatic malignant liver tumor

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Patients with malignant liver tumors 2. Patients who undergo or have undergone surgical resection at Tohoku University Hospital 3. Patients aged 18 years or older 4. For prospectively collected samples, patients who provide written informed consent to participate in this study

Exclusion criteria

Exclusion criteria: 1. Patients who have not been informed that they have a malignant tumor 2. Patients who are unable to voluntarily provide informed consent

Design outcomes

Primary

Measure	Time frame
Gene expression changes in host hepatocytes and stromal cells associated with malignant liver tumors, assessed by bulk RNA-seq and Xenium spatial gene expression analysis of surgically resected tissues	—

Secondary

Measure	Time frame
Associations between metabolite, cytokine, and peripheral blood mononuclear cell profiles in body fluid samples, including blood, and gene expression or spatial expression patterns in tissue samples	—

Countries

Japan

Contacts

Public ContactMayuko Yoda

Tohoku University Instutite of Development, Aging and Cancer

mayuko.yoda.e8@tohoku.ac.jp022-717-8568

Outcome results