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Incremental diagnostic value of pericoronary adipose tissue attenuation for the detection of vulnerable plaques

Incremental diagnostic value of pericoronary adipose tissue attenuation for the detection of vulnerable plaques - Incremental diagnostic value of pericoronary adipose tissue attenuation for the detection of vulnerable plaques

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
JPRN
Registry ID
JPRN-UMIN000061857
Enrollment
150
Registered
2026-06-10
Start date
2026-08-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute coronary syndrome

Interventions

None listed

Sponsors

Others
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Patients who developed acute coronary syndrome (ACS) due to plaque rupture as defined by percutaneous coronary intervention performed at the participating institutions between January 1, 2016 and December 31, 2025. 2. Patients in whom plaque rupture at the culprit lesion was identified by intravascular imaging, including intravascular ultrasound and/or optical coherence tomography, at the time of ACS. 2. Among the above patients, those who underwent coronary CT between 1 month and 2 years before the onset of ACS.

Exclusion criteria

Exclusion criteria: 1. Patients who developed ACS due to restenosis-related lesions. 2. Patients who underwent coronary artery bypass grafting. 3. Patients with inadequate image quality on coronary CT.

Design outcomes

Primary

MeasureTime frame
Whether the target lesion was identified as the ACS culprit lesion associated with plaque rupture

Secondary

MeasureTime frame
Differences in PCAT attenuation between ACS culprit lesions with plaque rupture and non-culprit lesions

Countries

Japan

Contacts

Public ContactTakayoshi Toba

Kobe University Graduate School of Medicine Division of Cardiovascular Medicine, Department of Internal Medicine

taka02222003@gmail.com078-382-5846

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026