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Study on the Feasibility and Safety of Early Mobilization Frequency in Patients With Aneurysmal Subarachnoid Hemorrhage

Feasibility and Safety of Increased Early Mobilization Frequency During the Vasospasm Period After Aneurysmal Subarachnoid Hemorrhage: A Single-Center Pilot Randomized Controlled Trial - SAFE-EM trial

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000061817
Enrollment
50
Registered
2026-06-06
Start date
2026-06-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

aneurysmal subarachnoid hemorrhage

Interventions

In the control group, early mobilization will be performed once daily according to the standardized early mobilization protocol of our hospital until day 14 after onset or discharge from the SCU, whic

Sponsors

Department of Rehabilitation, Tsuchiura Kyodo General Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Patients aged 18 years or older 2. Patients diagnosed with aneurysmal subarachnoid hemorrhage (aSAH) who have undergone definitive treatment for a ruptured aneurysm 3. Patients judged by the attending physician to be eligible for early mobilization and who meet the early mobilization initiation criteria of our hospital 4. Patients who provide written informed consent, or whose legally acceptable representative provides written informed consent

Exclusion criteria

Exclusion criteria: 1. Patients with untreated aneurysms, either ruptured or unruptured, for whom the attending physician considers early mobilization to pose safety concerns 2. Patients judged to be unable to undergo early mobilization because of hemodynamic instability or severe respiratory failure 3. Patients judged to be unable to undergo early mobilization because of conditions requiring sedation 4. Patients judged to be unable to undergo early mobilization because of increased intracranial pressure, uncontrolled intracranial bleeding, or severe stenosis or occlusion of the cerebral or cervical arteries 5. Patients or legally acceptable representatives who do not provide informed consent

Design outcomes

Primary

MeasureTime frame
Achievement rate of twice-daily early mobilization in the intervention group

Secondary

MeasureTime frame
Incidence of symptomatic cerebral vasospasm (SCV)

Countries

Japan

Contacts

Public ContactKenji Oike

Tsuchiura Kyodo General Hospital Department of Rehabilitation

ek296988@yahoo.co.jp029-830-3711

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026