Helthy skin
Conditions
Interventions
None listed
Sponsors
DRC
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: Women aged 20 years or older and under 60 years at the time of informed consent (target: approximately 50 subjects per age group) Healthy female subjects Subjects who have received sufficient explanation regarding the purpose and procedures of the study, possess the capacity to provide consent, fully understand the study, voluntarily agree to participate, and are able to provide written informed consent
Exclusion criteria
Exclusion criteria: Subjects with any condition at the evaluation site that may affect study results (e.g., urticaria, inflammation, eczema, wounds, acne, warts, pigmentation, or residual marks); those with a past or current history of atopic dermatitis or atopic predisposition (including family history); those who have received or plan to receive cosmetic medical procedures at the evaluation site (e.g., botulinum toxin, fillers, photofacial); those who have undergone or plan to undergo special skincare treatments (e.g., aesthetic/salon treatments) within 4 weeks; those who have changed or newly started health foods, skincare products, or sunscreen within 4 weeks; those with excessive UV exposure beyond daily life within 4 weeks or planned during the study; night shift or rotating shift workers; those receiving medical treatment at the time of consent or judged to require treatment; those with severe systemic diseases (metabolic, hepatic, renal, cardiovascular, respiratory, endocrine, immune, neurological); those with a history of alcohol or drug dependence; those at risk of allergy to cosmetics or foods (including skin reactions within 1 year); those who are pregnant, breastfeeding, or planning pregnancy; those who participated in other human studies within 4 weeks or plan to participate during the study; and those deemed unsuitable by the investigator.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Facial sagging analysis using Vectra Handy imaging Analysis of spots, wrinkles, pores, skin tone unevenness, porphyrins, subsurface pigmentation, melanin index, and hemoglobin index using VISIA Evolution imaging Pore analysis using Antera 3D imaging Microscopic imaging analysis Measurement of transepidermal water loss (TEWL) Measurement of stratum corneum hydration Measurement of skin viscoelasticity Tape stripping analysis, including cell area, multiple strippings, nucleated cell assessment, and skin metabolite-related markers with immunostaining Measurement of dermal thickness using DermaLab Pore analysis using skin replica sampling Measurement of sebum production Microbiome analysis based on skin sample collection | — |
Countries
Japan
Contacts
Public ContactMizuho Kokubo
ALBION CO., LTD. R&D Laboratory
Outcome results
None listed