Genetic Mutation Analysis of Lung Cancer Using Intraoperative Tumor Specimens

Genetic Mutation Analysis of Lung Cancer Using Intraoperative Tumor Specimens - Genetic Mutation Analysis of Lung Cancer Using Intraoperative Tumor Specimens

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000061792

Enrollment

800

Registered

2026-06-03

Start date

2025-03-13

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lung cancer

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) Patients aged 20 years or older at the time informed consent was obtained. 2) Patients who underwent surgical treatment for lung cancer. 3) Patients whose preoperative biopsy specimens, intraoperative RNA-preserved specimens, intraoperative FFPE specimens, and/or postoperative FFPE specimens were examined by multigene mutation testing under routine clinical practice covered by health insurance. 4) Patients from whom written informed consent for participation in this study was obtained.

Exclusion criteria

Exclusion criteria: Pattens who do not fulfill the inclusion criteria.

Design outcomes

Primary

Measure	Time frame
Detection rates of EGFR mutations in preoperative biopsy specimens, intraoperative specimens preserved in an RNA stabilization solution, and intra- and postoperative FFPE specimens	—

Secondary

Measure	Time frame
Detection rates of ALK fusions in preoperative biopsy specimens, intraoperative specimens preserved in an RNA stabilization solution, and intra- and postoperative FFPE specimens	—

Countries

Japan

Contacts

Public ContactKentaro Minegishi

Jichi Medical University Saitama Medical Center Department of General Thoracic Surgery

k-minegishi@jichi.ac.jp048-647-2111

Outcome results